For 23andMe migrants
The DNA file you downloaded from 23andMe is a real, useful artifact. The interpretation you got was not. Helica reads the same file and surfaces clinical-grade pharmacogenomic findings 23andMe never went deep on — without re-sequencing, without a new kit, without an ecosystem to sign up for.
Context — what changed
TTAM Research Institute (Anne Wojcicki’s nonprofit) acquired the assets in July 2025 and continues to operate the consumer service. Multiple state attorneys general challenged the data transfer; the court approved it.
If you’re reading this, you probably already downloaded your raw data. That file — genome_*.txt— is ~600,000 SNPs of real, usable genotype information. Helica reads it and gives you back the clinical depth that should have shipped in the first place.
Migration in 3 steps
In your 23andMe account, go to Settings → Browse Raw Data → Download. You'll get a file named genome_LASTNAME_FIRSTNAME_*.txt. That's the file we want.
On our upload screen, drop the .txt file directly. We parse it in seconds. Files are encrypted at rest. We never share or sell your data.
Free tier: ancestry, 5 traits, 2 PGx findings. Standard tier ($29/mo) unlocks the full PGx panel, carrier status, and the chat interface. Quarterly reanalysis rolls out at launch. No credit card on the free tier.
Same file. Different depth.
| Topic | 23andMe / TTAM | Helica |
|---|---|---|
| Pharmacogenomics depth | Limited — 1 to 3 PGx variants reported | Full CPIC core panel, every drug-metabolism gene that can be called from chip-array data |
| Source citations | Marketing summaries | CPIC guideline, ClinVar entry, or peer-reviewed paper, linked on every finding |
| Reanalysis | Infrequent in practice | Built for quarterly re-runs against latest ClinVar / CPIC / PGS Catalog (rolling out 2026) |
| Conversational interface | None — static dashboard | Ask plain-English questions; answers cite your specific variant rows |
| Doctor-printable summary | None | Clinician-facing PCP Handoff PDF in development for launch |
| Data ownership | Historic GSK research partnership pre-bankruptcy; TTAM nonprofit charter adds safeguards | Yours. We do not share without explicit, granular, revocable opt-in |
What a chip-array file actually returns
Most of the major CYP2C19 star alleles — the ones that matter for clopidogrel (Plavix), several SSRIs, and PPIs — are genotyped on the 23andMe v5 chip. We can confidently call your CYP2C19 phenotype from the file you already have.
Other genes (notably CYP2D6) have structural variants that chip arrays don’t capture fully. Helica is explicit per finding about confidence and source. We never invent results we can’t support with your data.
Intermediate Metabolizer
Reduced clopidogrel activation. Standard 75 mg dose may not produce sufficient antiplatelet effect after acute coronary syndrome or stenting.
Affected medications
Free tier
If your genome_*.txt is sitting in a Downloads folder, that's the starting point. Two findings free. No credit card.
We are not affiliated with 23andMe Holding Co. or TTAM. Helica reads the standard raw-data export format. Findings are informational and not a substitute for medical advice.